PDRN Skincare and Regenerative Beauty: Dr. Daniel Gould Featured in HuffPost

Beverly Hills plastic surgeon Dr. Daniel Gould, MD, PhD was recently featured in HuffPost discussing PDRN, an increasingly popular regenerative skincare ingredient, and several of the topical formulations bringing the technology into at-home skincare routines.

PDRN, short for polydeoxyribonucleotide, is composed of DNA fragments and has a history of use in regenerative medicine, particularly in South Korea. Interest in the ingredient has expanded rapidly within skincare because of its potential role in supporting tissue repair, hydration, collagen production, and overall skin quality.

In the article, Dr. Gould highlights the IOPE PDRN Caffeine Shot Serum, explaining that the PDRN used in this particular formulation is derived from green tea and plants. The serum pairs PDRN with ingredients including niacinamide, probiotics, and caffeine, combining regenerative-focused skincare with ingredients commonly used to support tone, barrier health, and the appearance of the skin.

Dr. Gould also discusses VT Cosmetics PDRN 100 Essence, a vegan formulation containing PDRN sourced from Korean ginseng. The product combines its PDRN technology with ingredients such as panthenol and ceramides, reflecting a broader trend toward formulations designed to support both regenerative pathways and the skin barrier.

Another format highlighted by Dr. Gould is Mediheal's PDRN sheet mask, which uses rose-derived PDRN alongside hydrating ingredients such as squalane. The variety of plant-derived and traditionally sourced PDRN products now entering the market demonstrates how quickly the ingredient is moving from a specialized regenerative concept into mainstream skincare.

As regenerative ingredients become increasingly prominent in aesthetic medicine and skincare, understanding the formulation and science behind a product remains important. PDRN represents one part of a broader movement toward skincare focused not simply on temporarily improving appearance, but on supporting the biological processes involved in healthier, more resilient skin over time.

Read the full article in HuffPost:
https://www.huffpost.com/entry/best-pdrn-beauty-products-2026-ud_l_6a60e374e4b0c2f78d012fd1?origin=home-shopping-feed-unit