Secretomes and the Future of Regenerative Skincare: Dr. Daniel Gould Featured in Air Mail

Beverly Hills plastic surgeon Dr. Daniel Gould, MD, PhD was featured in Air Mail’s LOOK in an article exploring secretomes, an emerging regenerative skincare treatment derived from a patient’s own cells and gaining attention within aesthetic medicine.

Secretomes represent a newer development in the growing field of regenerative aesthetics. Similar to platelet-rich plasma treatments, the approach uses biological material originating from the individual patient. However, rather than beginning with a blood draw, the process described by Air Mail starts with approximately 40 hairs collected from the scalp.

The cells associated with those hair follicles can be used to create a personalized secretome containing signaling molecules involved in cellular communication. This concept is part of a broader movement in aesthetic medicine toward treatments designed to work with the body’s own biological processes rather than relying exclusively on synthetic ingredients or traditional cosmetic interventions.

Interest in secretomes also reflects the evolution of regenerative skincare beyond established treatments such as platelet-rich plasma. As researchers and physicians learn more about cellular signaling, growth factors, exosomes, and other components involved in tissue repair, new technologies are emerging that aim to translate those mechanisms into treatments for skin quality and rejuvenation. Air Mail describes secretomes as one of the newest entrants into this regenerative beauty category.

For Dr. Gould, emerging regenerative technologies are best considered through the science behind them rather than the excitement surrounding a new treatment. Understanding where the biological material comes from, how it is processed, and what evidence supports its use is particularly important as regenerative aesthetics becomes an increasingly prominent part of modern skincare.

The growing interest in secretomes represents a larger shift in aesthetic medicine toward treatments focused not only on how skin appears, but also on the biological processes involved in maintaining and repairing it. As the field continues to develop, these technologies may become another component of a more comprehensive approach to supporting skin quality and long-term rejuvenation.

Read the full article in Air Mail:
https://airmail.news/look/issues/2025-11-7/skin-savior